Widespread cortical dyslamination in epilepsy patients with malformations of cortical development.
Eyal LotanOmri TomerIdo TavorIlan BlattHadassah Goldberg-SternChen HoffmannGalia TsarfatyDavid TanneYaniv AssafPublished in: Neuroradiology (2020)
Our results reveal widespread cortical abnormalities in epilepsy patients with FCD and PNH, which may have a role in epileptogenesis, and likely related to recent studies showing widespread structural (e.g., cortical thinning) and diffusion abnormalities in various human epilepsy populations. Our study provides quantitative information of cortical laminar architecture in epilepsy patients that can be further targeted for study in functional and neuropathological studies.