CircVMP1 promotes glycolysis and disease progression by upregulating HKDC1 in colorectal cancer.

Hong-Yu ChenXiang-Nan LiLei YangChun-Xiang YeZhi-Lei ChenZhen-Jun Wang

Published in: Environmental toxicology (2023)

Our study reported that circVMP1 was one of the tumor driver genes that promoted CRC malignant progression and glycolysis by upregulating HKDC1. CircVMP1/miR-3167/HKDC1 was a signaling axis that might be a target for CRC therapy.

Keyphrases

cell proliferation
long non coding rna
genome wide
gene expression
dna methylation
transcription factor
bioinformatics analysis