Long-term renal and cardiovascular risks of tacrolimus in patients with lupus nephritis.
Mieke van SchaikObbo W BredewoldMerel PriesterWieneke M MichelsTon J RabelinkJoris I RotmansY K Onno TengPublished in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association (2024)
Our study demonstrated that tacrolimus exposure was associated with long-term kidney function loss in LN patients. Although cardiovascular risk factors and events were similar to patients never exposed to tacrolimus, there may be an increased risk of developing diabetes. Therefore, our study supports vigilance towards renal adverse effects in LN patients treated with tacrolimus.