The Lysine Demethylase KDM5B Regulates Islet Function and Glucose Homeostasis.

Marie Balslev BackeChunyu JinLuz AndreoneAditya SankarKarl AggerKristian HelinAndreas Nygaard MadsenSteen Seier PoulsenMadhusudhan BysaniKarl BacosCharlotte LingMarcelo Javier PeroneBirgitte HolstThomas Mandrup-Poulsen

Published in: Journal of diabetes research (2019)

Our results show a novel role of KDM5B in metabolism, as KDM5B-KO mice display growth retardation and improved insulin sensitivity.

Keyphrases

blood glucose
blood pressure
amino acid
insulin resistance
skeletal muscle
weight loss