Metamizole: An underrated agent causing severe idiosyncratic drug-induced liver injury.

Marcial SebodeMartin Reike-KunzeSören WeidemannRoman ZenouziJohannes HartlMoritz PeiselerTimur LiwinskiLisa SchulzChristina Weiler-NormannMartina SterneckAnsgar W LohseChristoph Schramm

Published in: British journal of clinical pharmacology (2020)

Elevation of liver enzymes or acute liver failure are not mentioned in the German drug label of metamizole as potential side effects. Our study reveals that in Germany and Europe, metamizole is a frequent and underrated agent causing DILI.

Keyphrases

liver failure
drug induced
hepatitis b virus
adverse drug
early onset
emergency department
climate change
mechanical ventilation
aortic dissection