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The extracellular signal-regulated kinase 1/2 triggers angiogenesis in human ectopic endometrial implants by inducing angioblast differentiation and proliferation.

Sefa ArlierWilliam MurkOzlem Guzeloglu-KayisliNihan SemerciKellie LarsenMehmet S TabakAydin AriciFrederick SchatzCharles J LockwoodUmit Ali Kayisli
Published in: American journal of reproductive immunology (New York, N.Y. : 1989) (2017)
Enhanced ERK1/2 activity in angioblasts by such peritoneal factors as VEGF, E2 induces proliferation to trigger ectopic endometrial angiogenesis.
Keyphrases
  • endothelial cells
  • signaling pathway
  • vascular endothelial growth factor
  • endometrial cancer
  • pi k akt
  • transcription factor
  • tyrosine kinase
  • protein kinase
  • wound healing
  • soft tissue