Higher risk for chronic graft-versus-host disease (GvHD) in HLA-G mismatched transplants following allogeneic hematopoietic stem cell transplantation: A retrospective study.
Christine NeuchelSowmya GowdavallyChrysanthi TsamadouUwe PlatzbeckerElisa SalaEva Wagner-DrouetThomas ValeriusNicolaus KrögerGerald WulfHermann EinseleLorenz ThurnerKerstin Schaefer-EckartSebastian FreitagJochen CasperMareike DürholtMartin KaufmannBernd HertensteinStefan KleinMark RinghofferSandra FrankElisa Maria AmannImmanuel RodeHubert SchrezenmeierJoannis MytilineosDaniel FuerstPublished in: HLA (2022)
Our results indicate that HLA-G mismatches may contribute to the onset of chronic GvHD, especially in younger patients and should therefore be avoided when possible.