Low folate predicts accelerated cognitive decline: 8-year follow-up of 3140 older adults in Ireland.
Deirdre M A O'ConnorSiobhan ScarlettCéline De LoozeAisling M O'HalloranEamon LairdAnne M MolloyRobert ClarkeChristine Ann McGarrigleRose Anne KennyPublished in: European journal of clinical nutrition (2022)
In those aged ≥50 years, lower concentrations of folate may have differential relationships with cognitive domains. Folate <11.2 nmol/L predicted a decline in global cognitive function, while <21.8 nmol/L predicted poorer episodic memory. Low folate was associated with accelerated decline in cognitive function and is an important marker for cognitive decline among older people.