A rapid simple point-of-care assay for the detection of SARS-CoV-2 neutralizing antibodies.
Patthara KongsupholHuan JiaHoi Lok ChengYue GuBhuvaneshwari D/O ShunmuganathanMing Wei ChenSing Mei LimSay Yong NgPaul Ananth TambyahHaziq NasirXiaohong GaoDousabel TaySeunghyeon KimRashi GuptaXinlei QianMary M KozmaKiren PurushotormanMegan E McBeePaul A MacAryHadley D SikesPeter Rainer PreiserPublished in: Communications medicine (2021)
A rapid 10 min cellulose based test has been developed for detection of NAb against SARS-CoV-2. The test demonstrates comparable performance to the lab-based tests and can be used at Point-of-Care. Importantly, the approach used for this test can be easily extended to test RBD variants or to evaluate NAbs against other pathogens.