Outcome of severe COVID-19: spotlight on fatigue, fatigability, multidomain complaints and pattern of cognitive deficits in a case series without prior brain dysfunction and without COVID-19-related stroke and/or cardiac arrest.
Valérie BeaudSonia Crottaz-HerbetteVincent DunetJean-François KnebelPierre-Alexandre BartStephanie ClarkePublished in: Journal of medical case reports (2024)
Fatigue, fatigability, multidomain complaints, cognitive difficulties, or dysfunction, as well as isolated neurobehavioral and/or psychiatric and/or somatic symptoms, tend to occur in the aftermath of severe COVID-19 and persist at 12 months, even in the absence of prior and/or COVID-19-related brain damage. This clinical situation, which impacts everyday life, calls for a detailed investigation of patients' complaints, its neural underpinning, and an elaboration of specific rehabilitation programs.
Keyphrases
- coronavirus disease
- sars cov
- cardiac arrest
- oxidative stress
- end stage renal disease
- public health
- resting state
- ejection fraction
- sleep quality
- early onset
- white matter
- atrial fibrillation
- mental health
- newly diagnosed
- chronic kidney disease
- drug induced
- prognostic factors
- multiple sclerosis
- cerebral ischemia
- functional connectivity
- gene expression
- blood brain barrier
- patient reported