White matter abnormalities in healthy E200K carriers may serve as an early biomarker for genetic Creutzfeldt-Jakob disease (gCJD).

Nurit Omer Amgad DrobyRawan SilbakNoa TrablusAya Bar DavidTamara ShinerYifat AlcalayRoy AlcalayTalya NathanAvner ThalerAnat MirelmanMali Gana WeiszOrly GoldsteinTal GlinkaAvi Orr-UrtregerNir GiladiNoa Bregman

Published in: Journal of neurology, neurosurgery, and psychiatry (2024)

NCT05746715.

Keyphrases

white matter
multiple sclerosis
genome wide
copy number
gene expression