Single-nucleotide polymorphisms in a cohort of significantly obese women without cardiometabolic diseases.
Karen A SchlauchDoina KulickKrishnamurthy SubramanianKenny L De MeirleirAndrás PalotásVincent C LombardiPublished in: International journal of obesity (2005) (2018)
Our analysis identified 89 SNPs that reach statistical significance (p < 1 × 10-5), some of which are associated with genes of biological pathways that influences dietary behavior; others are associated with genes previously linked to obesity and cardiometabolic disease as well as neuroimmune disease. This study, to the best of our knowledge, represents the first genetic screening of a cardiometabolically healthy, but significantly obese population.