Novel cardiac extracellular matrix biomarkers in STEMI: Associations with ischemic injury and long-term mortality.
Simon AndrupGeir Ø AndersenPavel HoffmannJan EritslandIngebjørg SeljeflotSigrun HalvorsenMaria VistnesPublished in: PloS one (2024)
In patients with STEMI, we found an association between serum levels of ECM biomarkers and ischemic injury and mortality. The results provide new insight into the role ECM components play in ischemic injury following STEMI and suggests a potential for these biomarkers in prognostication after STEMI.
Keyphrases
- extracellular matrix
- st elevation myocardial infarction
- percutaneous coronary intervention
- st segment elevation myocardial infarction
- ischemia reperfusion injury
- cardiovascular events
- risk factors
- cerebral ischemia
- coronary artery disease
- left ventricular
- type diabetes
- cardiovascular disease
- oxidative stress
- blood brain barrier
- risk assessment
- subarachnoid hemorrhage