Gestational and lactational exposure to gossypol alters the testis transcriptome.

Helder LouvandiniPatricia S CorrêaRocío AmorínLihe LiuEgon H IedaCarolina R JimenezSiu M TsaiConcepta M McManusFrancisco Peñagaricano

Published in: BMC genomics (2020)

Our findings provide evidence that maternal exposure to gossypol alters male reproductive function in the offspring, with potential lasting or lifelong negative consequences.

Keyphrases

birth weight
weight gain
pregnancy outcomes
pregnant women
high fat diet
gene expression
rna seq
single cell
genome wide
gestational age
human health
body mass index
risk assessment
type diabetes
adipose tissue
metabolic syndrome
skeletal muscle
germ cell
preterm birth