A hybrid simulation model approach to examine bacterial genome sequencing during a hospital outbreak.

Thomas M ElliottXing J LeeAnna FoegleinPatrick N HarrisLouisa G Gordon

Published in: BMC infectious diseases (2020)

A hybrid simulation approach using the advantages of both agent-based and discrete-event modeling successfully replicated a real-life bacterial hospital outbreak as a foundation for evaluating clinical outcomes and efficiency of outbreak management. Whole genome sequencing of a potentially serious pathogen appears effective in containing an outbreak and minimizing hospital costs.

Keyphrases

healthcare
acute care
adverse drug
emergency department
gene expression
single cell
dna methylation