The Anti-Inflammatory Mediator 17(R)-Resolvin D1 Attenuates Pressure Overload-Induced Cardiac Hypertrophy and Fibrosis.
Menglong WangWei PanCheng WeiJianfang LiuJishou ZhangJunping YuMengmeng ZhaoShuwan XuJing YeZhen WangDi YeYongqi FengYao XuJun WanPublished in: Drug design, development and therapy (2023)
17(R)-RvD1 attenuated pressure overload-induced cardiac hypertrophy and fibrosis, and the possible mechanism may be associated with the inhibition of NLRP3 inflammasome. 17(R)-RvD1 may serve as a potential drug for the treatment of cardiac hypertrophy.