Neural correlates of episodic memory in adults with Down syndrome and Alzheimer's disease.

Bessy BenejamMateus Rozalem AranhaLaura VidelaConcepción PadillaSilvia ValldeneuSusana FernándezMiren AltunaMaria Carmona-IraguiIsabel BarroetaMaria Florencia IulitaVíctor MontalJordi PeguerolesAlexandre BejaninSandra GiménezSofía González-OrtizSebastián VidelaDavid Bartrés-FazDaniel AlcoleaRafael BlesaAlberto LleóJuan Fortea

Published in: Alzheimer's research & therapy (2022)

Different episodic memory measures were associated with cortical atrophy in specific brain regions in adults with Down syndrome and Alzheimer's disease. These results overlap with those described in sporadic Alzheimer's disease and further support the similarities between Down syndrome-associated Alzheimer's disease and that in the general population.

Keyphrases

cognitive decline
multiple sclerosis
late onset
brain injury
early onset