Hexokinase inhibition using D-Mannoheptulose enhances oncolytic newcastle disease virus-mediated killing of breast cancer cells.
Ahmed Ghdhban Al-ZiaydiAhmed Majeed Al-ShammariMohammed I HamzahHaider Sabah KadhimMajid Sakhi JabirPublished in: Cancer cell international (2020)
The combination treatment showed safe significant tumor cell proliferation inhibition compared to monotherapies suggesting a novel strategy for anti-breast cancer therapy through glycolysis inhibition by hexokinase downregulation.