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Evidence for both sequential mutations and recombination in the evolution of kdr alleles in Aedes aegypti.

Yinjun FanPatrick O'GradyMelissa YoshimizuAlongkot PonlawatPhillip E KaufmanJeffrey G Scott
Published in: PLoS neglected tropical diseases (2020)
Our data corroborated previous geographic distributions of resistance mutations and provided evidence for both recombination and sequential accumulation of mutations contributing to the molecular evolution of resistance alleles in A. aegypti.
Keyphrases
  • aedes aegypti
  • dna damage
  • zika virus
  • dna repair
  • dengue virus
  • big data
  • oxidative stress
  • single molecule
  • artificial intelligence