A novel imatinib-upregulated long noncoding RNA plays a critical role in inhibition of tumor growth induced by Abl oncogenes.

Yun MaGuijie GuoTingting LiFaxin WenJianling YangBiao ChenXuefei WangJi-Long Chen

Published in: Molecular cancer (2022)

These findings unveil an inhibitory role of lncRNA-IUR1 in Abl-mediated cellular transformation, and provide new insights into molecular mechanisms underlying Abl-induced leukemogenesis.

Keyphrases

long noncoding rna
chronic myeloid leukemia
tyrosine kinase
diabetic rats
high glucose
drug induced
long non coding rna
single molecule