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Outcomes of serum food-specific IgG4 to guide elimination diet in patients with eosinophilic esophagitis.

Amanda Huoy Wen LimBenjamin NgoiGriffith Boord PerkinsStephanie WongGail WhitelockPlinio Reinaldo HurtadoAndrew RuszkiewiczThanh-Thao Adriana LePravin HissariaNam Quoc Nguyen
Published in: The American journal of gastroenterology (2024)
Serum FS- IgG4 to milk, wheat, soy, egg and nuts were present at higher levels in EoE, with targeted elimination resulting in 45% histologic remission rate. Serum FS-IgG4 has potential as a non-invasive biomarker in EoE. When successful, FS-IgG4-led elimination diet can negate need for medications and be viewed more favourably by patients due to its smaller endoscopic burden compared to empirical elimination diets.
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