Low Frequency of MKRN3 and DLK1 Variants in Chinese Children with Central Precocious Puberty.

Ting Chen Linqi Chen Haiying Wu Rongrong Xie Fengyun Wang Xiuli Chen Hui Sun Fei Xiao

Published in: International journal of endocrinology (2019)

In this study, we report four novel MKRN3 variants in patients with ICPP. Moreover, we did not find any variants of DLK1 gene. Variants of MKRN3 are relatively uncommon in Chinese ICPP patients.

Keyphrases

copy number
end stage renal disease
chronic kidney disease
ejection fraction
newly diagnosed
young adults
peritoneal dialysis
dna methylation
prognostic factors
transcription factor