Cell sources of inflammatory mediators present in bone marrow areas inside the meniscus.
Francisco Airton Castro RochaVirgínia Claudia Carneiro GirãoRodolfo de Melo NunesAna Carolina Matias Dinelly PintoBruno VidalJoão Eurico FonsecaPublished in: PloS one (2019)
We provide novel data showing that rodent menisci display bone marrow areas with cells able to produce inflammatory mediators. Immunoexpression of inflammatory mediators in those bone marrow areas is significantly more pronounced in mice subjected to experimental OA.
Keyphrases
- bone marrow
- mesenchymal stem cells
- oxidative stress
- induced apoptosis
- cell therapy
- cell cycle arrest
- type diabetes
- electronic health record
- drinking water
- signaling pathway
- high fat diet induced
- machine learning
- stem cells
- cell death
- cell proliferation
- knee osteoarthritis
- skeletal muscle
- metabolic syndrome
- adipose tissue
- data analysis