Differential clinical significance of COL5A1 and COL5A2 in tongue squamous cell carcinoma.

Hung-Chih ChenYu-Kai TsengChih-Wen ShuTa-Jung WengHuei-Han LiouLiang-Ming YenI-Chien HsiehCheng-Ching WangPi-Chuan WuYow-Ling ShiueTing-Ying FuKuo-Wang TsaiLuo-Ping GerPei-Feng Liu

Published in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2019)

COL5A1 is an unfavorable factor for tumorigenesis, clinicopathological outcomes, and prognosis, whereas COL5A2 is only a favorable factor for prognosis in TSCC. The co-expression of high (COL5A1)2/low (COL5A2) heterotrimer is a more potential unfavorable factor for prognosis in TSCC.

Keyphrases

squamous cell carcinoma
type diabetes
metabolic syndrome
risk assessment
radiation therapy
climate change
binding protein
long non coding rna
human health