Novel inflammatory biomarkers in thyroid eye disease.

Hans Olav UelandGrethe Åstrøm UelandKristian LøvåsLars Ertesvåg BreivkAlexander Stanley ThraneAnn-Elin Meling StoklandEyvind RødahlEystein Sverre Husebye

Published in: European journal of endocrinology (2022)

We demonstrate an immunologic fingerprint of GD, as serum levels of several inflammation-related proteins were elevated, while others were decreased. Distinctly increased levels of IL6, CSF1, FLT3LG, and FGF21 were observed in TED, suggesting that these inflammatory proteins could be important in the pathogenesis, and therefore potential new biomarkers for clinical use.

Keyphrases

oxidative stress
acute myeloid leukemia
tyrosine kinase
human health
risk assessment
cerebrospinal fluid