Reduction of Immune Activation and Partial Recovery of Staphylococcal Enterotoxin B-Induced Cytokine Production After Switching to an Integrase Strand Transfer Inhibitor-Containing Regimen: Results from an Observational Cohort Study.
Esther MerliniFederico A CazzanigaAnna CasabiancaChiara OrlandiMauro MagnaniGiuseppe AnconaCamilla TincatiAntonella d'Arminio MonforteGiulia Carla MarchettiPublished in: Clinical drug investigation (2020)
Our data show a favorable effect of EVG/c/FTC/TDF switch to preserve immune activation-driven damage to T cell homeostasis, restore the multifunctional properties of effector T cells, and possibly contain cell-associated HIV viral burden in already virologically suppressed patients.
Keyphrases
- hiv infected
- end stage renal disease
- newly diagnosed
- ejection fraction
- sars cov
- chronic kidney disease
- hepatitis c virus
- prognostic factors
- single cell
- human immunodeficiency virus
- peritoneal dialysis
- hiv positive
- regulatory t cells
- electronic health record
- high glucose
- dendritic cells
- cell therapy
- hiv aids
- drug induced
- big data
- bone marrow
- artificial intelligence
- men who have sex with men
- data analysis