Comparison of Antibody-Dependent Cell-Mediated Cytotoxicity and Virus Neutralization by HIV-1 Env-Specific Monoclonal Antibodies.

Benjamin von BredowJuan F AriasLisa N HeyerBrian MoldtKhoa LeJames E RobinsonSusan Zolla-PaznerDennis R BurtonDavid T Evans

Published in: Journal of virology (2016)

This study provides fundamental insights into the relationship between antibody-dependent cell-mediated cytotoxicity (ADCC) and virus neutralization that may help to guide the development of antibody-based vaccines and immunotherapies for the prevention and treatment of HIV-1 infection.

Keyphrases

antiretroviral therapy
single cell
cell therapy
hiv infected
hiv positive
human immunodeficiency virus
hepatitis c virus
hiv aids
stem cells
bone marrow
men who have sex with men
combination therapy
smoking cessation