Prognostic impact of hypochromic erythrocytes in patients with pulmonary arterial hypertension.

Panagiota XanthouliVivienne TheobaldNicola BenjaminAlberto M MarraAnna D'AgostinoBenjamin EgenlaufMemoona ShaukatCao DingAntonio CittadiniEduardo BossoneMaria KöglerEkkehard GrünigMartina U MuckenthalerChristina A Eichstaedt

Published in: Respiratory research (2021)

The presence of hypochromic erythrocytes > 2% was a strong and independent predictor of mortality and shorter TTCW in this cohort of PAH patients. Thus, it can serve as a valuable indicator of iron homeostasis and prognosis even in patients without iron deficiency or anemia. Further studies are needed to confirm the results and to investigate therapeutic implications.

Keyphrases

end stage renal disease
pulmonary arterial hypertension
iron deficiency
chronic kidney disease
ejection fraction
newly diagnosed
prognostic factors
cardiovascular disease
pulmonary artery
type diabetes