Exosomal circPACRGL promotes progression of colorectal cancer via the miR-142-3p/miR-506-3p- TGF-β1 axis.
Anquan ShangChenzheng GuWeiwei WangXuan WangJunjun SunBingjie ZengChen ChenWenjing ChangYili PingPing JiJunlu WuWenqiang QuanYiwen YaoYongxin ZhouZujun SunDong LiPublished in: Molecular cancer (2020)
Our study, the first to reveal that cancer-derived exosomal circPACRGL plays an oncogenic role in CRC proliferation and metastasis, providing mechanistic insights into the roles of circRNAs in CRC progression and a valuable marker for CRC treatment.