Login / Signup

TP53 loss-of-function causes vulnerability to autophagy inhibition in aggressive prostate cancer.

Yong ZhangXian-Li SongBin YuLian-Chee FoongYu ShuChun Wai MaiJing HuBaijun DongWei XueChee Wai Chua
Published in: International journal of urology : official journal of the Japanese Urological Association (2022)
Our results support the potential use of autophagy inhibitors in prostate cancers that contain TP53 loss-of-function mutations.
Keyphrases
  • prostate cancer
  • cell death
  • endoplasmic reticulum stress
  • radical prostatectomy
  • signaling pathway
  • oxidative stress
  • risk assessment