Subcutaneous panniculitis-like T-cell lymphoma: an unusual cause of right thigh hypertrophy.
Mahmoud Husni Ayesh Haj YousefSohaib M Al-KhatibRuba A KhasawnehLaith RahabnehPublished in: BMJ case reports (2022)
A man in his mid-20s presented with a painless swelling over his right thigh, which had been progressively increasing over 3 years. He underwent an excisional biopsy for the same, which showed reactive lymphadenopathy. Since the last year and a half, he developed a lower abdominal wall swelling with mild redness over it. In addition, over the last few months before presentation to haematology outpatient clinic, he experienced bouts of fever, night sweats, anorexia, weight loss and right inguinal lymphadenopathy. On examination, splenomegaly was identified. In view of the patients' symptoms, he underwent a positron emission tomography scan, which showed hypermetabolic activity in the subcutaneous tissue sparing the lymph nodes and spleen. A deep skin punch biopsy taken from his right thigh was consistent with the diagnosis of subcutaneous panniculitis-like T-cell lymphoma αβ T-cell phenotype. The patient was treated successfully with oral steroids and on routine follow-up, he is in remission for 5 years.
Keyphrases
- positron emission tomography
- computed tomography
- fine needle aspiration
- soft tissue
- lymph node
- weight loss
- end stage renal disease
- newly diagnosed
- ejection fraction
- case report
- ultrasound guided
- chronic kidney disease
- primary care
- bariatric surgery
- peritoneal dialysis
- prognostic factors
- magnetic resonance imaging
- pet imaging
- type diabetes
- sleep quality
- rheumatoid arthritis
- body mass index
- disease activity
- physical activity
- skeletal muscle
- magnetic resonance
- clinical practice
- early stage
- systemic lupus erythematosus
- neoadjuvant chemotherapy
- depressive symptoms
- glycemic control
- rectal cancer
- contrast enhanced
- sentinel lymph node