Serum IL-36 cytokines levels in type 2 diabetes mellitus patients and their association with obesity, insulin resistance, and inflammation.
Yan LiSisi ChenTingqi ZhaoMingcai LiPublished in: Journal of clinical laboratory analysis (2020)
This study demonstrated that T2DM patients displayed increased IL-36α and IL-36γ expression and decreased IL-36Ra expression. Moreover, the inflammatory cytokine levels were directly proportional to the inflammation and blood lipid levels. Our results suggest that IL-36 cytokines may be a new target for the diagnosis or treatment of T2DM.
Keyphrases
- insulin resistance
- end stage renal disease
- ejection fraction
- newly diagnosed
- oxidative stress
- type diabetes
- prognostic factors
- peritoneal dialysis
- rheumatoid arthritis
- skeletal muscle
- systemic lupus erythematosus
- binding protein
- body mass index
- high fat diet
- idiopathic pulmonary fibrosis
- systemic sclerosis
- smoking cessation