A single-domain antibody detects and neutralises toxic Aβ 42 oligomers in the Alzheimer's disease CSF.
Alessandra BigiLiliana NapolitanoDevkee M VadukulFabrizio ChitiCristina CecchiFrancesco A AprileRoberta Cascella
Published in: Alzheimer's research & therapy (2024)
Taken together, our data indicate a promising method for the improvement of an early diagnosis of AD and for the generation of novel therapeutic approaches based on sdAbs for the treatment of AD and other devastating neurodegenerative conditions.