Insulin-like growth factor binding protein-2 and glucose-regulated protein 78 kDa: Potential biomarkers affect prognosis in IDH-wildtype glioblastoma patients.

Abigail J Harland Claire Marie Perks Paul White Kathreena M Kurian Hannah R Barber

Published in: Cancer medicine (2023)

Inverse levels of IGFBP-2 and GRP78 may be adverse clinical prognostic markers in IDH-wildtype glioblastoma. Further interrogation of the mechanistic link between IGFBP-2 and GRP78 may be important for rationalisation of their potential as biomarkers and therapeutic targets.

Keyphrases

binding protein
end stage renal disease
chronic kidney disease
ejection fraction
newly diagnosed
low grade
endoplasmic reticulum stress
prognostic factors
transcription factor
peritoneal dialysis
metabolic syndrome
wild type
blood glucose
protein protein
patient reported
heat shock protein
small molecule
amino acid