Login / Signup

Protective effects of oyster polypeptide from oyster (Crassostrea ariakensis) on cyclophosphamide induced immunosuppression rats based on 1 H NMR metabolomics and 16S rRNA gene sequencing.

Ying HeYunyuan NongJunliang QinLinlin FengJinghua QinQianyi WangLijun DengSiqi TangMeiling ZhangXiaofeng FanMin DongJinbin WeiShihan PanZhi-Heng Su
Published in: Journal of the science of food and agriculture (2024)
This study demonstrated that OP had immunoprotective effects in cyclophosphamide-induced immunosuppression rats by restoring key metabolic pathways and the gut microbiome homeostasis. Our findings provides a framework for further research into the immunoregulatory mechanisms of OP and its potential use in drugs and nutritional supplements. This article is protected by copyright. All rights reserved.
Keyphrases
  • high glucose
  • diabetic rats
  • low dose
  • drug induced
  • magnetic resonance
  • high resolution
  • mass spectrometry
  • endothelial cells
  • oxidative stress
  • genome wide
  • transcription factor