Intestinal Epithelia and Myeloid Immune Cells Shape Colitis Severity and Colorectal Carcinogenesis via High-mobility Group Box Protein 1.

Katharina FoelschPenelope PelczarElisabeth ZierzStephanie KondratowiczMinyue QiChristian MuellerMalik AlawiSina HuebenerTill ClauditzNicola GaglianiSamuel HuberPeter Huebener

Published in: Journal of Crohn's & colitis (2024)

Enterocytes and myeloid cells context-dependently regulate host responses to severe colitis and maladaptive intestinal wound healing via HMGB1.

Keyphrases

wound healing
induced apoptosis
dendritic cells
bone marrow
acute myeloid leukemia
cell cycle arrest
binding protein
transcription factor
early onset
amino acid
endoplasmic reticulum stress
protein protein
cell death
signaling pathway
small molecule
immune response
drug induced