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Zinc protects against lead-induced testicular damage via modulation of steroidogenic and xanthine oxidase/uric acid/caspase 3-mediated apoptotic signaling in male Wistar rats.

E E BesongP J AshonibareO O ObembeM A FolawiyoD H AdeyemiM A HamedT M AkhigbeRoland Eghoghosoa Akhigbe
Published in: The aging male : the official journal of the International Society for the Study of the Aging Male (2023)
This study demonstrated that zinc protected against lead-induced testicular toxicity via the downregulation of XO/UA/caspase 3 signaling.
Keyphrases
  • uric acid
  • cell death
  • high glucose
  • diabetic rats
  • oxidative stress
  • metabolic syndrome
  • induced apoptosis
  • drug induced
  • germ cell
  • signaling pathway
  • endothelial cells