The maternal age-related first trimester risks for trisomy 21, 18 and 13 based on Danish first trimester data from 2005 to 2014.

Tanja Schlaikjaer HartwigSteen SørensenFinn Stener Jørgensen

Published in: Prenatal diagnosis (2016)

We found that the age-related risks are better described by sigmoidal functions, contrary to the widely assumed exponential functions. Our results indicate a lower age-related a priori risk of T21, T18 and T13 compared to widely used risk models. © 2016 John Wiley & Sons, Ltd.

Keyphrases

human health
electronic health record
risk assessment
birth weight
big data
pregnancy outcomes
climate change
pregnant women
body mass index