Sex steroid hormones and risk of breast cancer: a two-sample Mendelian randomization study.

Aayah NounuSiddhartha P KarCaroline L ReltonRebecca C Richmond

Published in: Breast cancer research : BCR (2022)

TT, BT, DHEAS and estradiol increase the risk of ER+ type BCs similar to observational studies. Understanding the role of sex steroid hormones in BC risk, particularly subtype-specific risks, highlights the potential importance of attempts to modify and/or monitor hormone levels in order to prevent BC.

Keyphrases

estrogen receptor
risk assessment
endoplasmic reticulum