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Acute encephalopathy followed by delayed myelopathy: A rare presentation of organophosphate poisoning.

Ayush AgarwalDivyani GargVinay GoyalVishnu VyMamta Bhushan SinghMv Padma Srivastava
Published in: Tropical doctor (2020)
Organophosphorus compounds (OPC) are commonly used pesticides and suicidal ingestion is a common mode of poisoning. The manifestation of OPC poisoning and its severity depend upon the type, dose and potency of the OPC consumed. Neurological presentations are well defined clinical syndromes consisting of early, intermediate and delayed manifestations (rare), categorised on the basis of time elapsed since OPC exposure. We report a rare delayed manifestation of organophosphorus poisoning in the form of pure motor spastic paraparesis due to dorsal myelopathy. A possibility of delayed manifestations of toxicity should be considered in individuals presenting with features suggestive of myelopathy and a previous history of organophosphate exposure.
Keyphrases
  • spinal cord
  • neuropathic pain
  • risk assessment
  • liver failure
  • depressive symptoms
  • oxidative stress
  • early onset
  • drug induced
  • respiratory failure
  • cerebral palsy
  • tandem mass spectrometry
  • liquid chromatography