Distinct Patterns of Hippocampal Pathology in Alzheimer's Disease with TDP-43.
Grace MinogueAllegra KawlesAntonia ZouridakisRachel KeszyckiAlyssa MacomberVivienne LubbatNathan GillQinwen MaoMargaret E FlanaganHui ZhangRudolph CastellaniEileen H BigioM-Marsel MesulamChangiz GeulaTamar GefenPublished in: Annals of neurology (2023)
We conclude that AD/TDP can be distinguished from AD and FTLD-TDP based on differential regional distributions of hippocampal tau and TDP-43. Findings suggest that tau aggregation in AD/TDP may be enhanced by TDP-43. This article is protected by copyright. All rights reserved.