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Peritoneal carcinomatosis after risk-reducing surgery in BRCA1/2 mutation carriers.

Marline G HarmsenJurgen M J PiekJohan BultenMurray J CaseyTimothy R RebbeckMarian J MouritsMark H GreeneBrigitte F M SlangenMarc van BeurdenLeon F A G MassugerNicoline HoogerbruggeJoanne A de Hullu
Published in: Cancer (2018)
Metachronous peritoneal carcinomatosis after risk-reducing surgery occurs predominantly in BRCA1 mutation carriers, usually within 5 years. Data have suggested that surgery at a younger age lowers the rates of peritoneal carcinomatosis. These data can be used in the gynecologic counseling of BRCA1/2 mutation carriers. RRSO should include complete salpingectomy. Detailed histopathological examination of specimens removed during RRSO is essential. Cancer 2018;124:952-9. © 2018 American Cancer Society.
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