Effect of caffeine on hippocampal memory and levels of gene expression in social isolation stress.

Seval Musuroglu KeloglanLeyla SahinSayad KocahanEbru AnnacNurhan TirasciAyper Boga Pekmezekmek

Published in: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience (2023)

SI impaired spatial memory and causes morphological changes in adolescent rats, but this effect of isolation was not seen in Cf-treated animals. The effects of SI on NR2A, Cf on NR2B, and SNAP25 are remarkable. Here, we propose that the impaired effect of SI on spatial memory may be mediated by NR2A, but further studies are needed to explain this effect.

Keyphrases

gene expression
working memory
cystic fibrosis
room temperature
mental health
young adults
stress induced
blood brain barrier