Borane-Pyridine: An Efficient Catalyst for Direct Amidation.

P Veeraraghavan RamachandranAman G SinghHarry WalkerHenry J Hamann

Published in: Molecules (Basel, Switzerland) (2024)

Borane-pyridine acts as an efficient (5 mol%) liquid catalyst, providing improved solubility for the direct amidation of a wide range of aromatic and aliphatic carboxylic acids and amines to form secondary and tertiary carboxamides. Tolerance of potentially incompatible halo, nitro, and alkene functionalities has been demonstrated.

Keyphrases

ionic liquid
room temperature
reduced graphene oxide
highly efficient
carbon dioxide
metal organic framework
visible light
gold nanoparticles