Castanea sativa Mill. bark extract exhibits chemopreventive properties triggering extrinsic apoptotic pathway in Jurkat cells.

Monia LenziMarco MalagutiVeronica CocchiSilvana HreliaPatrizia Hrelia

Published in: BMC complementary and alternative medicine (2017)

Our data suggest that CSM bark extract might be considered an interesting potential anti-cancer agent, since it induces apoptosis in cancer cells without appreciable cytotoxic effects on non-transformed cells.

Keyphrases

induced apoptosis
cell cycle arrest
oxidative stress
cell death
anti inflammatory
signaling pathway
endoplasmic reticulum stress
machine learning
electronic health record
pi k akt
climate change
artificial intelligence
data analysis