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Pharmacological properties of TRPM3 isoforms are determined by the length of the pore loop.

Katharina HeldVincenzo Davide AloiAna Cristina Nogueira FreitasAnnelies JanssensAndrei SegalJulia PrzibillaStephan Ernst PhilippYu Tian WangThomas VoetsJoris Vriens
Published in: British journal of pharmacology (2020)
Alternative splicing in the pore-forming region of TRPM3 defines the channel's pharmacological properties, which depend critically on the length of the pore-forming loop.
Keyphrases
  • transcription factor