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DNMT1 in Six2 Progenitor Cells Is Essential for Transposable Element Silencing and Kidney Development.

Szu-Yuan LiJiwhan ParkYuting GuanKiwung ChungRojesh ShresthaMatthew B PalmerKatalin Suszták
Published in: Journal of the American Society of Nephrology : JASN (2019)
Genome-wide cytosine methylation and gene expression profiling showed that by silencing embryonic, nonrenal lineage genes and transposable elements, DNMT1-mediated cytosine methylation is essential for kidney development.
Keyphrases
  • genome wide
  • dna methylation
  • copy number
  • gene expression
  • genome wide identification
  • single cell