Identification of an EMT-related Gene Signature Predicting Recurrence in Stage II/III Colorectal Cancer: A Retrospective Study in 1780 Patients.

Haoyu RenFlorian BöschElise PretzschSven JacobC Benedikt WestphalenJulian Walter HolchJens WernerMartin K Angele

Published in: Annals of surgery (2022)

The identified ERG signature is a promising and powerful biomarker predicting recurrence in CRC patients. Moreover, the presented ERG signature might help to stratify patients according to their tumor biology and contribute to personalized treatment.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
gene expression
dna methylation
patient reported outcomes
epithelial mesenchymal transition
transcription factor
copy number
signaling pathway
drug induced