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Gene fusions in vascular tumors and their underlying molecular mechanisms.

Sheena Li Ming OngKároly SzuhaiJudith V M G Bovée
Published in: Expert review of molecular diagnostics (2021)
The identification of gene fusions in a subset of vascular tumors over the past decade has improved diagnostic accuracy, and has provided the pathologists with novel diagnostic tools to accurately diagnose these often difficult tumors. Moreover, the increased understanding of the underlying molecular mechanisms can guide the development of targeted therapeutic strategies.
Keyphrases
  • copy number
  • genome wide
  • genome wide identification
  • transcription factor
  • genome wide analysis