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Melatonin prevents glyphosate-induced hepatic lipid accumulation in roosters via activating Nrf2 pathway.

Shu-Hui ZhangHai-Jing ZhangYan-Zhan JiaZhen-Yong WangZhao-Hong YouCai-Yu LianLin Wang
Published in: International immunopharmacology (2024)
Collectively, our results provide the first direct evidence that MET is a novel regulator of Nrf2, highlighting that Nrf2 may be a potential therapeutic target for GLY-induced lipotoxic liver injury.
Keyphrases
  • drug induced
  • liver injury
  • oxidative stress
  • diabetic rats
  • high glucose
  • transcription factor
  • endothelial cells
  • tyrosine kinase